Glyphosate [N-(phosphonomethyl)glycine] toxicity to volunteer wheat (Triticum aestivum L.) and large crabgrass [Digitaria sanguinalis (L.) Scop. # DIGSA] was influenced more by carrier volume than application method. Glyphosate phytotoxicity increased when carrier volume was reduced with both application methods. When compared at equal carrier volumes, there was little difference in volunteer wheat or large crabgrass control when glyphosate was applied with a controlled droplet applicator or flat fan nozzles. Volunteer wheat and large crabgrass control with controlled droplet applicators was influenced by application factors. At a given carrier volume, application factors which yielded larger droplets generally resulted in superior vegetation control.