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1 results

  • An Open-Source Storage Solution for Cryo-Electron Microscopy Samples

  • Part of
  • Eveline Ultee, Fred Schenkel, Wen Yang, Susanne Brenzinger, Jamie S. Depelteau, Ariane Briegel
  • Journal:
    Microscopy and Microanalysis / Volume 24 / Issue 1 / February 2018
    Published online by Cambridge University Press:
    18 January 2018, pp. 60-63
    Print publication:
    February 2018

  • Cryo-electron microscopy (cryo-EM) enables the study of biological structures in situ in great detail and to solve protein structures at Ångstrom level resolution. Due to recent advances in instrumentation and data processing, the field of cryo-EM is a rapidly growing. Access to facilities and national centers that house the state-of-the-art microscopes is limited due to the ever-rising demand, resulting in long wait times between sample preparation and data acquisition. To improve sample storage, we have developed a cryo-storage system with an efficient, high storage capacity that enables sample storage in a highly organized manner. This system is simple to use, cost-effective and easily adaptable for any type of grid storage box and dewar and any size cryo-EM laboratory.