Extragalactic maser sources are unique tools to derive fundamental physical quantities of the host galaxies, e.g, geometry of accretion disks around super-massive black holes and precise black hole masses, and study in detail the interaction region of nuclear jets/outflows with the interstellar medium, in nearby and distant Active Galactic Nuclei. So far, however, extragalactic maser searches have yielded detection of few percent, and only relatively few maser sources have been found. Because of their unprecedented sensitivity, new upcoming facilities, like the SKA and the ngVLA, will allow to significantly increase the number of known (water) maser sources. This will lead to the chance of performing statistically-relevant studies of the maser phenomenon (and its occurrence), derive extragalactic masers luminosity functions, and ultimately (in particular, through the aid of longer-baselines arrays options) to perform the studies described above for larger samples and up to cosmological distances.