One of the main objectives of astrobiology is to understand the distribution of life in the universe, for microbial life, as well as for the search of extra-terrestrial intelligence, both of which would force upon us new problems in philosophy, including ethics and theology. The question of astrobiology and the humanities being such a broad topic, in the present paper we have limited our discussion of the Frontiers of Astrobiology and the Humanities to the single topic: ‘Independence of science (astrobiology) from philosophy and theology’. We have argued along the lines of this narrower thesis, but restricting our theological discussion strictly to a Judeo-Christian perspective.