Distinctive Lutheran and Reformed theologies of the relationship between Word and Spirit influenced the history of Protestant exegesis of 1 Corinthians 2:13, which states, ‘we speak not in words taught by human wisdom, but in those taught by the Spirit’. The interpretation of the time of the Spirit's teaching (past or present) and the identity of the words taught (scripture or preaching/teaching) are seen to depend upon and develop these respective Lutheran and Reformed theologies. The essay concludes with a brief evaluation of the adequacy of these interpretations in light of the divine economy and some ecumenical considerations.