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Chapter 8 - Some Aspects of the Lower Motor Neuron Syndrome
Robert Laureno, Georgetown University, Washington DC
Book:

Insights into Clinical Neurology

Published online:

27 July 2023

Print publication:

20 July 2023, pp 48-51
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Summary

Disease of the lower motor neuron causes a decrease in strength and myotatic reflexes. Involved muscle shows weakness and twitching. The latter is of two types, fibrillation and fasciculation. Fibrillation is due to spontaneous depolarization of single muscle fiber. Fasciculation is due to spontaneous depolarization of the many muscle fibers of a motor unit. As a rule, fibrillation is pathological. Fasciculation may be pathological or benign.