We evaluated the effects of selective slow-wave
sleep (SWS) deprivation and time-of-night factors on cognitive
performance upon awakening. Ten normal men slept for 6
consecutive nights in the laboratory: 1 adaptation, 2 baseline,
2 selective SWS deprivation, and 1 recovery night. Cognitive
performance was assessed by means of a Descending Subtraction
Task after 2, 5, and 7.5 h of sleep. There was an almost
complete selective SWS suppression during both deprivation
nights, and a significant SWS rebound during the recovery
sleep. Regarding cognitive performance, a progressive linear
decrease of sleep inertia upon successive awakenings was
found during all experimental nights except for the recovery
night. In addition, a significant decrease of sleep inertia
was observed upon the morning awakening of the second deprivation
night for the measure of performance speed, and a significant
increase of sleep inertia upon the morning awakening of
the recovery night for the measure of performance accuracy.
The results show that cognitive performance upon awakening
is adversely affected by sleep depth and that, during the
sleep–wake transition, cognitive performance accuracy
is more impaired than performance speed.