This study compares the relative thermal damage caused by a surgical CO2 laser and the Erbium: YAG laser when used to incise the human vocal fold in vitro. Results show that charring is completely eliminated when using the Erbium: YAG laser. The depth of coagulative necrosis adjacent to an incision is reduced from 510 ±m(µ 75) using the CO2 laser to 23 ±m(µ 12) using the Ebrium: YAG laser and at the base is reduced from 125 ±m (µ 45) using the CO2 laser to 12 ±m (µ 8 ) using the Erbium: YAG laser. The potential advantages regarding post-operative healing after laryngeal surgery are discussed.