Delayed production can substantially alter the qualitative behaviour of feedback systems. Motivated by stochastic mechanisms in gene expression, we consider a protein molecule which is produced in randomly timed bursts, requires an exponentially distributed time to activate and then partakes in positive regulation of its burst frequency. Asymptotically analysing the underlying master equation in the large-delay regime, we provide tractable approximations to time-dependent probability distributions of molecular copy numbers. Importantly, the presented analysis demonstrates that positive feedback systems with large production delays can constitute a stable toggle switch even if they operate with low copy numbers of active molecules.

In the paper, relativistic self-focusing in the interaction of laser beam and plasma with periodical density ripple has been studied by the applied WKB approximation and higher-order paraxial theory. The result shows that under the influence of relativistic nonlinear effect, the dielectric function shows the fierce oscillational variation with similar periodicity, which then leads to the intense relativistic beam self-focusing along the propagation distance, such self-focusing also presents similar periodic variation. Besides, in the plasma with periodical density ripple, the initial density and the density ripple amplitude have obvious influence on self-focusing. When the two factors increase, then there will be more strength self-focusing. Choosing the appropriate initial density and the periodic density parameter is benefit to the formation of the more stable self-focusing.

In this paper we present a fast and accurate numerical algorithm for the computation of hyperspherical Bessel functions of large order and real arguments. For the hyperspherical Bessel functions of closed type, no stable algorithm existed so far due to the lack of a backwards recurrence. We solved this problem by establishing a relation to Gegenbauer polynomials. All our algorithms are written in C and are publicly available at Github [https://github.com/lesgourg/class_public]. A Python wrapper is available upon request.

We consider rotating flows of an electrically conducting, viscous and resistive fluid in an external magnetic field with arbitrary combinations of axial and azimuthal components. Within the short-wavelength approximation, the local stability of the flow is studied with respect to perturbations of arbitrary azimuthal wavenumbers. In the limit of vanishing magnetic Prandtl number (Pm) we find that the maximum critical Rossby number (Ro) for the occurrence of the magnetorotational instability (MRI) is universally governed by the Liu limit ${\rm Ro}_{Liu}=2-2\sqrt{2}\approx -0.828$ which is below the value for Keplerian rotation RoKepler = −0.75.