Field experiments were carried out from 1987 to 1990 to develop an integrated weed control management system for the control of blackgrass in winter wheat in Greece. The weed control treatments included both herbicides and cultural measures. The performance of preemergence (PRE) herbicides against blackgrass was better than postemergence (POST) herbicides; selectivity was dependent on application rate. Late timing of wheat sowing resulted in significant reduction of the blackgrass population competing with wheat. The critical period for blackgrass infestation occurred 4.0 to 5.5 wk after wheat emergence. Blackgrass density of 170 to 1,170 plants/m2 caused wheat yield reduction equal to 10 and 30%, respectively. A quadratic relationship describing the percent reduction of wheat yield due to competition with different blackgrass densities was developed. The economic threshold level for blackgrass varied between 100 and 125 plants/m2. The results emphasize the importance of using a combination of chemical and cultural controls, including critical periods for herbicide application in maintaining an integrated approach for blackgrass control in wheat.