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2 results

  • Dobutamine-induced Takotsubo syndrome in a paediatric heart transplant patient

  • Ezequiel Sagray, Jonathan N. Johnson, Jason H. Anderson
  • Journal:
    Cardiology in the Young / Volume 33 / Issue 4 / April 2023
    Published online by Cambridge University Press:
    28 July 2022, pp. 646-648
    • Article
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  • Takotsubo syndrome is a potentially reversible cause of acute systolic dysfunction. Takotsubo syndrome is rare in children, with no reported dobutamine-induced cases to date. We present a 14-year-old male with prior history of heart transplantation, who developed Takotsubo syndrome during dobutamine stress echocardiography. We highlight the importance of its early recognition to ensure supportive measures with avoidance of inotropic medications.

  • Management of airway obstruction with nebulised adrenaline resulting in takotsubo cardiomyopathy: case report

  • F Keshtkar, O T Dale, W O Bennett, C E Hall
  • Journal:
    The Journal of Laryngology & Otology / Volume 130 / Issue 9 / September 2016
    Published online by Cambridge University Press:
    05 July 2016, pp. 883-886
    Print publication:
    September 2016
  • Background:

    Takotsubo cardiomyopathy has been associated with the use of catecholamines; however, its development after the use of nebulised adrenaline for the management of acute airway obstruction has not previously been described.

    Case report:

    A 66-year-old man with squamous cell carcinoma of the larynx, with tumour–node–metastasis staging of T3N2cM0, confirmed by biopsy and computed tomography, presented to the emergency department with acute airway obstruction. He was treated twice with nebulised adrenaline and intravenous dexamethasone. After a period of 24 hours, cardiac rhythm changes were noted on telemetry. A 12-lead electrocardiogram showed widespread T-wave inversion and QT prolongation suggestive of an acute coronary syndrome. Coronary angiography demonstrated no coronary artery disease, but left ventricular angiography showed marked apical ballooning and apical wall akinesia consistent with a diagnosis of takotsubo cardiomyopathy.

    Conclusion:

    Takotsubo cardiomyopathy can mimic true ischaemic heart disease and the diagnosis requires a high index of suspicion in patients managed with nebulised adrenaline.