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1 results

  • Long-term effects of allergen-specific subcutaneous immunotherapy for house dust mite induced allergic rhinitis

  • E Sahin, D Dizdar, M E Dinc, A A Cirik
  • Journal:
    The Journal of Laryngology & Otology / Volume 131 / Issue 11 / November 2017
    Published online by Cambridge University Press:
    17 October 2017, pp. 997-1001
    Print publication:
    November 2017
  • Background:

    Allergic rhinitis is strongly associated with the presence of house dust mites. This study investigated the long-term effects of allergen-specific immunotherapy. Allergen-specific immunotherapy was applied over three years. The study was based on a 10-year follow up of patients with allergic rhinitis.

    Methods:

    The study was conducted between 2001 and 2015. Skin prick test results and symptom scores were evaluated before (26 patients) and after 3 years (20 patients) of allergen-specific immunotherapy (using data from a previously published study), and 10 years after allergen-specific immunotherapy had ended (20 of 26 patients).

    Results:

    The symptom scores before allergen-specific immunotherapy were significantly higher than those obtained after 3 years of allergen-specific immunotherapy and 10 years after allergen-specific immunotherapy (p < 0.0175). There were no significant differences between the scores obtained at 3 years and 10 years after allergen-specific immunotherapy (p > 0.0175).

    Conclusion:

    Subcutaneous immunotherapy is an effective treatment for house dust mite induced allergic rhinitis.