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sperm fusion

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1 results

Sperm penetration in parthenogenetic mouse embryos triggers a plasma membrane block to polyspermy
Marek Maleszewski, Anna Bielak
Journal:

Zygote / Volume 1 / Issue 3 / August 1993

Published online by Cambridge University Press:

26 September 2008, pp. 237-242
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Mouse oocytes activated parthenogenetically do not generate a plasma membrane block against spermatozoa over the first three cell cycles. We show that they lose this fusibility spontaneously at the 8-cell stage. Insemination of 1-cell parthenogenetic embryos induces loss of fusibility earlier, at the 2-cell stage. This observation suggests that incorporation of the sperm cell membrane components into the oolemma may be responsible for the development of the membrane block.