Safflower (Carthamus tinctorius L. ‘Hartman’) in the rosette growth stage or early bolting stage tolerated thiameturon {3-[[[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino] carbonyl] amino] sulfonyl]-2-thiophenecarboxylic acid} at 5, 10, and 15 g ai/ha. Safflower also tolerated chlorsulfuron {2-chloro-N-[[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)amino] carbonyl] benzenesulfonamide} at 18 g/ha if safflower was taller than 15 cm at time of application. The fresh weight of above-ground biomass of common sunflower (Helianthus annuus L. #3 HELAN), treated at two plant sizes with thiameturon, was reduced more than 88%. Soil activity of thiameturon also reduced the seedling vigor of common sunflower, but thiameturon in soil was not as lethal to common sunflower as were foliar applications.