Glyphosate [N-(phosphonomethyl)glycine] was applied at various stages of maturity to corn (Zea mays L. ‘Pioneer brand 3147’ and ‘Dekalb XL 394’), soybeans [Glycine max (L.) Merr. ‘Forrest’ and ‘Essex’], and johnsongrass [Sorghum halepense (L.) Pers.]. Glyphosate applied over-the-top of corn before the grain moisture level decreased to 30% (black layer will have been formed) caused various seed and subsequent progeny abnormalities. Depending on grain moisture level at the time of glyphosate application, seed weight was sometimes reduced and progeny seedling emergence, vigor, and weight were reduced. Also, abnormal seedlings, albino or straited, occurred. Glyphosate applied 2½ weeks or more before soybean maturity reduced seed weight, caused seed discoloration, and drastically reduced progeny seedling emergence, vigor, and weight. Glyphosate applied in September or early October controlled semimature johnsongrass. Later applications were less effective because of advanced senescence.