This paper considers the impact of the Younger Dryas on the prehistoric inhabitants of Pont d'Ambon, a site in the Dordogne region of southwestern France, through an examination of the zooarchaeological remains from this site. An investigation of patch choice indicates that patch choice evenness declines during the Younger Dryas due to increasing local dominance of the grassland patch. Analyses of demographic composition, cutmark frequency, and marrow processing in the wild European rabbit (Oryctolagus cuniculus) assemblage suggest intensified rabbit use during this period. This study thus supports the hypothesis that changing climate had significant impacts on the prehistoric inhabitants of Pont d'Ambon. However, the traditional climate hypothesis—that changing climate negatively impacted the availability of larger fauna, forcing a switch to smaller, lower-ranked prey items—is not supported here. The inhabitants of Pont d'Ambon seem to have adapted to changing climate by efficiently exploiting the new species available to them, and possibly, during the Younger Dryas, by intensifying their use of one of these new species, the European rabbit.