In the late 1940s and early 1950s, as the US launched the Point Four initiative of overseas technical assistance programmes, a number of American officials, academics, and analysts saw valuable global lessons in the US Bureau of Indian Affairs’ development interventions among Native Americans. These interests culminated in a suite of professional training experiments, involving trainees from around the world, which emphasized cross-cultural development methods and used certain south-western Native American communities as field ‘laboratories’. A foundational seminar programme, coordinated by Cornell University social scientists, inspired additional training initiatives, tied to Point Four projects abroad, which brought foreign government officers from South Asia and the Middle East for similar training in New Mexico and Arizona. These training experiments not only placed Native American situations at the centre of significant transnational conversations about development, but also reinforced and widely circulated particular ideas regarding ‘underdevelopment’, ‘experts” prerogatives, and the politics of development relations.