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2 results

  • Rhinitis symptoms and quality of life in patients with chronic perennial rhinitis treated with desloratadine

  • H C K Lam, M C F Tong, C A Van Hasselt
  • Journal:
    The Journal of Laryngology & Otology / Volume 121 / Issue 12 / December 2007
    Published online by Cambridge University Press:
    19 July 2007, pp. 1151-1155
    Print publication:
    December 2007
  • Objective:

    To evaluate the outcome and the change in quality of life of patients with chronic rhinitis after treatment with desloratadine.

    Study design:

    A prospective, open-label, non-blinded, non-randomised study of patients in a secondary and tertiary ENT referral centre.

    Methods:

    Chinese patients with chronic rhinitis were recruited. The patients were assessed by a questionnaire that included rhinitis symptoms score and SF-36 health survey components. Endoscopic assessment was performed with a rigid nasoendoscope and scored according to the modified endoscopic appearance score of Lund and Kennedy. A 12-week course of desloratadine 5 mg daily was prescribed. Patients were re-evaluated after treatment. A total of 47 subjects completed the study.

    Results:

    There were significant reductions in median rhinitis symptoms score, from six to five (p < 0.001), and in median endoscopic appearance score, from five to three (p < 0.001). Patients' general health perception was also improved after treatment (p == 0.022).

    Conclusion:

    Desloratadine may be an effective treatment which provides symptomatic relief and improves the quality of life in patients with chronic rhinitis.

  • A comparison of partial inferior turbinectomy and cryosurgery for hypertrophic inferior turbinates

  • Yoseph Rakover, Gabriel Rosen
  • Journal:
    The Journal of Laryngology & Otology / Volume 110 / Issue 8 / August 1996
    Published online by Cambridge University Press:
    29 June 2007, pp. 732-735
    Print publication:
    August 1996

  • A variety of surgical procedures are performed for treatment of hypertrophic inferior turbinates, but there is no completely effective therapy. We evaluated subjectively and objectively 52 patients who underwent one of two procedures: partial inferior turbinectomy (PIT) or cryosurgery of the inferior turbinates (CS). The results of PIT showed good functional results in 77 per cent of cases for long-term effectiveness. The results of CS showed that effectiveness was reduced from a 62 per cent success rate after one year to 35 per cent later, but CS was a simple procedure which was performed on an outpatient basis with no postoperative morbidity.