The effectiveness of preharvest applications of glyphosate on yellow toadflax was evaluated at five sites in Alberta from 1992 to 1994. At each site, glyphosate at 0.9 to 1.8 kg ae/ha was applied with or without nonionic surfactant and/or ammonium sulfate. Glyphosate at 2.7 kg/ha and glufosinate at 0.6 kg ai/ha were applied without additional adjuvants. The treatments were applied 7 to 10 d before crop harvest, when the majority of the yellow toadflax was in a flowering stage. Eleven to 12 mo after glyphosate application, yellow toadflax density was reduced by more than 80%. In most instances, there was no advantage in increasing the glyphosate rate above 0.9 kg/ha. The addition of nonionic surfactant and/or ammonium sulfate did not enhance glyphosate activity. Glufosinate did not control yellow toadflax in the year following treatment. Barley, canola, and flax yields in the year following applications were significantly higher in all preharvest glyphosate-treated plots than in untreated plots.