Finite Cartesian products of operators play a central role in monotone operator theory and its applications. Extending such products to arbitrary families of operators acting on different Hilbert spaces is an open problem, which we address by introducing the Hilbert direct integral of a family of monotone operators. The properties of this construct are studied, and conditions under which the direct integral inherits the properties of the factor operators are provided. The question of determining whether the Hilbert direct integral of a family of subdifferentials of convex functions is itself a subdifferential leads us to introducing the Hilbert direct integral of a family of functions. We establish explicit expressions for evaluating the Legendre conjugate, subdifferential, recession function, Moreau envelope, and proximity operator of such integrals. Next, we propose a duality framework for monotone inclusion problems involving integrals of linearly composed monotone operators and show its pertinence toward the development of numerical solution methods. Applications to inclusion and variational problems are discussed.