Tycho is one of nearly a dozen Galactic supernova remnants which are suggested to emit hadronic γ-ray emission. Among them, however, it is the only one in which the hadronic emission is proposed to arise from the interaction with low-density ambient medium. Based on the multi-band observations, we suggest that Tycho is encountering dense cloud at the northeastern boundary. The γ-ray emissions can be explained by hadronic process with self-consistent parameters, such as a modest energy conversion efficiency. In this SNR-cloud association scenario, the distance can be estimated as ~2.5 kpc.