Sequences of non-decreasing (non-increasing) lower (upper) bounds for the renewal-type equation as well as for the renewal function which are improvements of the famous corresponding bounds of Marshal [(1973). Linear bounds on the renewal function. SIAM Journal on Applied Mathematics 24(2): 245–250] are given. Also, sequences such bounds converging to the ordinary renewal function are obtained for several reliability classes of the lifetime distributions of the inter-arrival times, which are refinements of all of the existing known corresponding bounds. For the first time, a lower bound for the renewal function with DMRL lifetimes is given. Finally, sequences of such improved bounds are given for the ordinary renewal density as well as for the right-tail of the distribution of the forward recurrence time.

In a discrete-time renewal process {Nk, k = 0, 1, ·· ·}, let Zk and Ak be the forward recurrence time and the renewal age, respectively, at time k. In this paper, we prove that if the inter-renewal time distribution is discrete DFR (decreasing failure rate) then both {Ak, k = 0, 1, ·· ·} and {Zk, k = 0, 1, ·· ·} are monotonically non-decreasing in k in hazard rate ordering. Since the results can be transferred to the continuous-time case, and since the hazard rate ordering is stronger than the ordinary stochastic ordering, our results strengthen the corresponding results of Brown (1980). A sufficient condition for {Nk+m – Nk, k = 0, 1, ·· ·} to be non-increasing in k in hazard rate ordering as well as some sufficient conditions for the opposite monotonicity results are given. Finally, Brown's conjecture that DFR is necessary for concavity of the renewal function in the continuous-time case is discussed.

Additional theory important in the design and evaluation of a periodic screening program is presented. The distributions of doubly bounded preclinical state forward and backward recurrence times of the stochastic screening model are derived. Properties of these distributions are used to obtain an expression for estimating the mean lead time gained by screening, an alternative theoretical expression for the mean lead time and an equation for calculating an estimate of the probability of detecting preclinical disease.

A stochastic model for a periodic screening program is presented in which the natural history of a chronic disease is assumed to follow a progressive path from a preclinical state to a clinical state. The sampling of preclinical state sojourn times by screening examinations generates bounds on the preclinical state recurrence times. The distribution of the bounded forward recurrence time is derived and used to obtain the distribution and mean of the lead time, and relationships for calculating the proportion of preclinical cases detected. These expressions are derived in terms of the preclinical state sojourn-time distribution and adjustible parameters important in the design of a periodic screening program.

Examples are given of point processes that are non-stationary but have stationary forward recurrence time distributions. They are obtained by modification of stationary Poisson and renewal processes.

Consider a Poisson point process with an intensity parameter forming a Markov chain with continuous time and finite state space. A system of ordinary differential equations is derived for the conditional distribution of the Markov chain given observations of the point process. An estimate of the current intensity, optimal in the least-squares sense, is computed from this distribution. Applications to reliability and replacement theory are given. A special case with two states, corresponding to a process in control and out of control, is discussed at length. Adjustment rules, based on the conditional probability of the out of control state, are studied. Regarded as a function of time, this probability forms a Markov process with the unit interval as state space. For the distribution of this process, integro-differential equations are derived. They are used to compute the average long run cost of adjustment rules.