Sleep-related vehicle accidents are prevalent early
morning, especially in younger drivers. In two independent
studies following a night of either restricted or nil sleep,
young experienced drivers drove for 2 hr (0600–0800h)
continuously in an immobile car on an interactive, computer-generated,
dull, and monotonous roadway. This exercise followed ingestion
(at 0530h) of 200 mg caffeine (= 2–3 cups coffee)
versus placebo, counterbalanced, double blind. Driving
incidents (lane drifting), subjective sleepiness, and 4–11
Hz electroencephalogram (EEG) activity were logged. In
Study 1 (sleeping 0000–0500h), caffeine significantly
reduced incidents and subjective sleepiness throughout
the 2-hr drive, and EEG power for the second 30-min period.
In Study 2 (no sleep), sleepiness affected all measures
profoundly, and driving was terminated after 1 hr. Nevertheless,
caffeine reduced incidents significantly for the first
30 min and subjective sleepiness for the hour. This caffeine
dose, feasibly taken via coffee, effectively reduces early
morning driver sleepiness for about 30 min following nil
sleep, and for around 2 hr after sleep restriction.