Live oak (Quercus virginiana Mill. # QUEVM) on the Texas Coastal Prairie was treated with herbicides using ground and aerial application methods. Tebuthiuron {N-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]-N,N′-dimethylurea} and pellets of buthidazole {3-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]-4-hydroxy-1-methyl-2-imidazolidinone} at 2.2 kg ai/ha were the most effective herbicides, killing 60 to 95% of the live oak. Tebuthiuron pellets 3.2 mm in diam were more effective than the wettable powder at 1.1 kg/ha. Bay Met 1486 {N-[5-(ethylsulfonyl)-1,3,4-thiadiazole-2-yl]-N,N′-dimethylurea}, Dowco 290 (3,6-dichloropicolinic acid), hexazinone [3-cyclohexyl-6-(dimethylamino)-1-methyl-1,3,5-triazine-2,4(1H, 3H)-dione], and picloram (4-amino-3,5,6-trichloropicolinic acid) reduced the live oak canopy at 2.2 kg/ha whereas 2,4,5-T [(2,4,5-trichlorophenoxy)acetic acid] and triclopyr {[(3,5,6-trichloro-2-pyridinyl)oxy] acetic acid} were ineffective. Foliage-active herbicides generally were most effective in reducing the live oak canopy during the year of application. The soil-active herbicides generally were most active 1 or 2 yr after herbicide application. All herbicides reduced the live oak cover sufficiently to allow an increase in grass cover 2 to 4 months after treatment. Tebuthiuron at 2.2 kg/ha maintained a high degree of grass cover at least 2 or 3 yr after treatment.