High resolution multiproxy analysis (microcharcoal, pollen, organic carbon, Neogloboquadrina pachyderma (s), ice rafted debris) of the deep-sea record MD04-2845 (Bay of Biscay) provides new insights for understanding mechanisms of fire regime variability of the last glacial period in western France. Fire regime of western France closely follows Dansgaard–Oeschger climatic variability and presents the same pattern than that of southwestern Iberia, namely low fire regime associated with open vegetation during stadials including Heinrich events, and high fire regime associated with open forest during interstadials. This supports a regional climatic control on fire regime for western Europe through fuel availability for the last glacial period. Additionally, each of Heinrich events 6, 5 and 4 is characterised by three episodes of fire regime, with a high regime bracketed by lower fire regime episodes, related to vegetational succession and complex environmental condition changes.