Asulam applied POST alone and in mixtures with residual herbicides and with DSMA and MSMA was evaluated for johnsongrass control. Johnsongrass control following treatment with asulam at 3.7 kg ai ha−1 was not improved by tank mixtures with the residual herbicides atrazine, metribuzin, pendimethalin, and terbacil compared with asulam applied alone. Johnsongrass injury symptoms appeared sooner when asulam was applied in mixtures with either DSMA or MSMA, but johnsongrass control 4 wk after treatment was similar to asulam applied alone. As a result of the johnsongrass control obtained with early POST treatments of asulam applied alone, cane and sugar yields were increased by 56 and 58%, respectively, when compared with the weedy check. Additional cane and sugar yield increases were not obtained by any of the asulam mixtures because johnsongrass control was not improved. Asulam applied again in May to johnsongrass regrowth improved late-season control in two of the three studies over a single early POST application, but cane and sugar yields were not increased.