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breast conservation

Journal of Radiotherapy in Practice (1)

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Breast conservation surgery and radiation for a patient with synchronous primary breast cancers and BRCA1/BRCA2 positivity: is mastectomy required?
Mark Trombetta, Katherine Kotinsley, Thomas B. Julian
Journal:

Journal of Radiotherapy in Practice / Volume 11 / Issue 1 / March 2012

Published online by Cambridge University Press:

18 March 2011, pp. 62-65
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The role of breast conservation in patients expressing BRCA1 and BRCA2 genetic mutations is controversial. A patient who was found to have bilateral synchronous breast cancers and expressed a BRCA genetic mutation was recently evaluated. The patient had a strong desire for breast preservation. This case and a review of the pertinent literature are presented to discuss the role of breast conservation and radiation in patients with BRCA1 or BRCA2 genetic mutations.