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ascertainment at birth

Acta geneticae medicae et gemellologiae: twin research (1)

International Soc for Twin Studies (1)

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Is Weinberg's Differential Rule Valid?
William H. James
Journal:

Acta geneticae medicae et gemellologiae: twin research / Volume 28 / Issue 1 / January 1979

Published online by Cambridge University Press:

01 August 2014, pp. 69-71

Print publication:

January 1979
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Weinberg's differential method, whereby the frequency of dizygotic twins in a population is obtained by doubling the number of opposite-sexed pairs, might not be valid. Data are presented indicating a higher frequency of same-sexed than opposite-sexed pairs among samples of dizygotic twins ascertained at birth, thus favoring the hypothesis that, contrary to the method's fundamental assumption, the sexes of the two twin zygotes be not independent.