Mandevilla (Apocynaceae) is a neotropical genus which is well represented in Brazil. A recent taxonomic revision of the Brazilian species of Mandevilla subgenus Mandevilla included eight new species, one of them from the State of Pernambuco. Nevertheless, while preparing a survey of Apocynaceae from the Brazilian semi-arid region, a new species of the subgenus was recognised. Mandevilla catimbauensis Souza-Silva, Rapini & J.F.Morales is here described and illustrated. It is a twining plant with elliptic, glabrous leaves and hypocrateriform, purple flowers, known only from the Vale do Catimbau National Park, in the State of Pernambuco.