During your overnight call duty, a 37-year-old G2P1 with a spontaneous pregnancy presents to the obstetrics emergency assessment unit of your tertiary center at 32+3 weeks’ gestation with pruritis preventing her from sleep. She has no obstetric complaints; cardiotocography initiated upon the patient’s presentation shows a normal fetal heart tracing and uterine quiescence.

A 23-year-old primigravida is referred to your high-risk obstetrics clinic at 17+3 weeks’ gestation for a reactive VDRL test on routine prenatal screening. Although her appointment with you is in two days, she presents urgently to your office for new-onset tongue lesions and a rash. She had an early dating sonography, and aneuploidy screening was unremarkable. She takes prenatal vitamins and has no obstetric complaints.

You are on obstetrics call duty at a community hospital center, where a 30-year-old G2P1 elementary schoolteacher presents concerned, after receiving notification during this spring week holiday, that there is an outbreak of ‘slapped cheek syndrome’ among the children. The patient is at 16+3 weeks’ gestation by dating sonography performed by her primary care provider; first-trimester fetal morphology was normal with a low risk of aneuploidy. Three years ago, she had a healthy pregnancy and term vaginal delivery of her son, who currently attends daycare. The patient does not have any obstetric complaints.