The ancient city of Alexandria was often referred to as Alexandria ad Aegyptum in Roman documentary, epigraphic and literary sources; this phrase was translated in Greek as ἡ Ἀλεξάνδρεια ἡ πρὸς Αἰγύπτῳ. The grammatical phrasing implies that Alexandria was seen as being ‘near’ or ‘next to’ Egypt, not ‘in’ Egypt. This observation has given rise to the scholarly view that Alexandria was not part of Egypt. In this article the function of the designation ad Aegyptum and of similar designations within literary, papyrological and epigraphic sources ranging from 300 b.c.e. to 640 c.e. will be closely examined. This article argues that the expression can be seen as reflecting both the distinction and the close connection between Alexandria and Egypt on the basis of geographical, political and socio-cultural factors.