This paper presents an aeromechanics investigation of tiltrotor aircraft through the conversion regime of flight. The effects of the rotors-on-wing, rotors-on-empennage and wing-on-empennage interactions were investigated singularly and collectively to assess their impacts on trim behaviour, performance and conversion boundaries. The rotors-on-wing download was found to be dominant in the prediction of hover and low-speed flight performance and had a degrading effect overall. The fuselage pitch attitude and stick position were found to be significantly affected by the empennage interaction cases throughout the conversion domain. The large flap/flaperon settings used to alleviate the rotor download contributed considerably to the low-speed trim behaviour. The conversion boundaries were found to be insensitive to all the interaction cases, though the min-speed boundary was reduced marginally due to the wing-on-empennage interaction. The results showed that the combined interactions were important factors to accurately predict the trim behaviour and aircraft performance throughout the conversion corridor.