When applied correctly, atrazine can be used safely in certain areas of the United States for weed control in winter wheat, but persistence in the soil may injure wheat replanted after crop failure. Studies were conducted at Moro, OR, in 1989–90 and 1990–91 to determine the effect of September preplant applications of atrazine at 0.56, 1.12, and 2.24 kg a.i. ha-1 (1X, 2X, and 4X label rates) on wheat seeded at that time and on wheat re-seeded 2 or 6 mo later. Yield of winter wheat re-seeded in November following September atrazine applications was not reduced at any rate. The September-planted wheat was killed with glyphosate in the spring to simulate winter killing, then plots were re-seeded to spring wheat. The commercial rate of atrazine, 0.56 kg ha-1, caused only minor injury to spring wheat, but injury at the 2X and 4X rates was excessive.