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The use of Naloxone During the Withdrawal Syndrome from Heroin

Published online by Cambridge University Press:  02 January 2018

D. N. Vlissides
Affiliation:
Department of Psychiatry, University of Sheffield and Royal Hallamshire Hospital
F. A. Jenner*
Affiliation:
Department of Psychiatry, Royal Hallamshire Hospital, Sheffield
I. A. Liappas
Affiliation:
Department of Psychiatry, University of Athens and Eginition Hospital, Athens
*
University Department of Psychiatry, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF

Abstract

Attempts to repeat in human subjects animal studies in which naloxone stopped withdrawal symptoms after prolonged use of heroin failed. Nevertheless, suggestions for further studies are made, as the subjects' subsequent desire for opiates did seem attenuated.

Type
Brief Reports
Copyright
Copyright © Royal College of Psychiatrists, 1988 

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References

Blachly, P. H. (1976) Naloxone in opiate addiction. Current Psychiatric Therapy, 16, 209213.Google Scholar
Hendrie, C. A. (1985) Marked attenuation of behavioural and non-receptive responses to morphine withdrawal by the opiate antagonist naloxone. Pharmacology, Biochemistry and Behaviour, 23, 863870.CrossRefGoogle Scholar
Kurland, A. A. & McCabe, L. (1976) Rapid detoxification of the narcotic addict with naloxone hydrochloride. Journal of Clinical Pharmacology, 16, 6775.Google Scholar
Resnick, R. B., Kestenbaum, R. S., Washton, A. & Poole, D. (1977) Naloxone precipitated withdrawal. A method for rapid induction onto naltrexone. Clinical Pharmacology and Therapeutics, 21, 409413.Google Scholar
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