Hostname: page-component-78c5997874-v9fdk Total loading time: 0 Render date: 2024-11-19T07:13:11.370Z Has data issue: false hasContentIssue false

Screening for Psychiatric Morbidity in Subjects Presenting with Chronic Fatigue Syndrome

Published online by Cambridge University Press:  02 January 2018

Anne Farmer*
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Helen Chubb
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Irene Jones
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Janis Hillier
Affiliation:
Department of Psychological Medicine, University of Wales College of Medicine
Andy Smith
Affiliation:
Department of Psychology, University of Bristol, 8 Woodland Road, Bristol, BS8 1TN
Leszek Borysiewicz
Affiliation:
Department of Medicine, University Hospital of Wales, Heath Park, Cardiff, CF4 4XN
*
Dr A. Farmer, Department of Psychological Medicine, University of Wales College of Medicine, Heath Park, Cardiff CF4 4XN

Abstract

Background

There is a need for a valid self-rating questionnaire to screen for psychiatric morbidity in patients with chronic fatigue syndrome (CFS). This study had the aim of assessing the utility and validity of two commonly used measures.

Method

Scores obtained on the General Health Questionnaire (GHQ) and the Beck Depression Inventory (BDI) were compared with various diagnostic and severity ratings obtained via a validating clinical interview, the Schedules for the Clinical Assessment of Neuropsychiatry (SCAN) in 95 consecutively referred subjects at a medical out-patient clinic who fulfilled standard criteria for CFS, and 48 healthy controls. Outcome measures were validating coefficients and receiver operating characteristics (ROC) for different thresholds and scoring on GHQ and BDI and index of definition (ID) as measured by SCAN; and Pearson and point by serial correlation coefficients for different diagnostic groups derived via SCAN and defined according to ICD–10 and DSM–III–R.

Results

GHQ and BDI perform poorly as screeners of psychiatric morbidity in CFS subjects when compared with various SCAN derived ratings although results for controls are comparable with other studies.

Conclusions

Neither the GHQ nor BDI alone can be recommended as screeners for psychiatric morbidity in CFS subjects.

Type
Research Article
Copyright
Copyright © 1996 The Royal College of Psychiatrists 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

American Psychiatric Association (1987) Diagnostic and Statistical Manual of Mental Disorders (3rd edn, revised) (DSM–III–R). Washington, DC: APA.Google Scholar
Beck, A. (1967) Depression: Clinical Experimental and Theoretical Aspects. New York: Hoeber.Google Scholar
Farmer, A. E., Jones, L., Hillier, J., et al (1995) Neurasthenia revisited: ICD–10 and DSM–III–R disorders in subjects with chronic fatigue and a comparison group. British Journal of Psychiatry, 167, 503507.CrossRefGoogle Scholar
Finlay-Jones, R. A. & Murphy, E. (1979) Severity of psychiatric disorder and the 30-item General Health Questionnaire. British Journal of Psychiatry, 134, 609616.Google Scholar
Fukada, K., Straus, S. E., Hickie, I., et al (1994) The Chronic Fatigue Syndrome: a comprehensive approach to its definition and study. Annals of Internal Medicine, 121, 953959.Google Scholar
Goldberg, D. (1978) The General Health Questionnaire (60-item). Windsor: NFER-Nelson Publishing Company.Google Scholar
Goldberg, D. & Williams, P. (1988) A User's Guide to the General Health Questionnaire. Windsor: NFER-Nelson.Google Scholar
Hanley, L. A. & McNeil, B. J. (1983) A method of comparing the areas under receiver operating characteristic curves derived from the same cases. Radiology, 148, 839843.Google Scholar
Lloyd, A., Hickie, I., Brockman, A., et al (1993) Immunologic and psychologic therapy for patients with chronic fatigue syndrome. A double-blind placebo-controlled trial. American Journal of Medicine, 94, 197203.Google Scholar
Schluederberg, A., Straus, S. E., Peterson, P., et al (1992) Chronic fatigue syndrome research. Definition and medical outcome. Annals of Internal Medicine, 117, 325331.Google Scholar
Wing, J. K., Cooper, J. E. & Sartorius, N. (1974) The Measurement and Classification of Psychiatric Symptoms. Cambridge: Cambridge University Press.Google Scholar
Wing, J. K., & Sturt, E. (1978) The PSE-ID-CATEGO System Supplementary Manual. Mimeograph MRC Social Psychiatry Unit. Institute of Psychiatry: London.Google Scholar
Wing, J. K., Babor, T., Brugha, T., et al (1990) SCAN: Schedules for Clinical Assessment in Neuropsychiatry. Archives of General Psychiatry, 47, 589593.Google Scholar
World Health Organization (1993) The Tenth Revision of the International Classification of Diseases and Related Health Problems (ICD–10): Diagnostic Criteria for Research. Geneva: WHO.Google Scholar
Submit a response

eLetters

No eLetters have been published for this article.