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Acute Hepatic Necrosis Following Treatment with Amitriptyline and Diazepam

Published online by Cambridge University Press:  29 January 2018

M. L. Cunningham*
Affiliation:
Springfield Huspital, Beechcroft Road, Upper Tooting, S.W.17

Extract

Among the numerous reports on toxic side effects of antidepressant drugs, the monoamine oxidase inhibitors appear prominent in causing such a variety of serious complications (4) that many physicians prefer to avoid their use altogether, and prefer other drugs (such as the Iminodibenzyl group) that produce their euphoriant effects more slowly but also more safely.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1965 

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References

1. Ayd, F. J. (1962). “Frank aids to medicine.” Brit. med. J. 1, 568.Google Scholar
2. Burkett, E. A., and Sutcliffe, C. K. (1961). “Paralytic ileus after Tryptizol.” Brit. med. J., 2, 1648.CrossRefGoogle Scholar
3. Burt, C. G., Gordon, W. F., Holt, N. F., and Hordern, A. (1963). “Amitriptyline in depressive states.” Brit. J. Psychiat., 109, 815825.Google Scholar
4. Burt, C. G., Gordon, W. F., Holt, N. F., and Hordern, A. (1964). Dunlop Committee Report on Adverse Reactions of MAOI.Google Scholar
5. Gander, D. R., and Devlin, H. B. (1963). “Ileus after amitriptyline.” Brit. med. J., 1, 1160.CrossRefGoogle Scholar
6. Gander, D. R., and Devlin, H. B. (1962). “Hepatotoxicity of drugs.” Lancet, 1, 1056.Google Scholar
7. Isaacs, A. D., and Carlish, N. (1963). “Peripheral neuropathy after amitriptyline.” Brit. med. J., 1, 1739.Google Scholar
8. Nimmo Smith, R. C., and Grieve, R. C. (1963). “Peripheral neuropathy after amitriptyline.” Brit. med. J., 2, 254.CrossRefGoogle Scholar
9. Nimmo Smith, R. C., and Grieve, R. C. (1961). “To-days drugs.” Brit. med. J., 2, 1492.Google Scholar
10. Nimmo Smith, R. C., and Grieve, R. C. (1963). “To-days drugs.” Brit. med. J., 1, 173.Google Scholar
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