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Neuroleptic Malignant Syndrome in Striatonigral Degeneration

Published online by Cambridge University Press:  02 January 2018

W. R. G. Gibb
W. R. G. Gibb*
Affiliation:
Department of Neuropathology, National Hospitals for Nervous Diseases, Maida Vale
*
∗National Hospitals for Nervous Diseases, Queen Square, London WC1N 3BG
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Abstract

A case of probable neuroleptic malignant syndrome (NMS) complicating l-dopa withdrawal in striatonigral degeneration is described. This case suggests that the hyperthermia of NMS is due to peripheral heat production associated with severe muscular rigidity secondary to withdrawal of striatal dopamine drive, rather than being centrally mediated by the hypothalamus, which is not involved in striatonigral degeneration.

Type
Brief Reports
Information
The British Journal of Psychiatry , Volume 153 , Issue 2 , August 1988 , pp. 254 - 255
Copyright
Copyright © Royal College of Psychiatrists, 1988 

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References

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