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Effects of Serum from Schizophrenics on Evoked Cortical Potentials in the Rat

Published online by Cambridge University Press:  29 January 2018

G. A. German*
Affiliation:
University of Aberdeen, and Psychiatry, Ross Clinic, Aberdeen

Extract

Many experiments have been reported suggesting that the serum of schizophrenic patients differs in some way from the serum of non-schizophrenic subjects, either in respect of some specific constituent or of the alterations in function which it can produce when added to various biological systems (Heath, 1957; Walaszek, 1960; Bergen, Koella, Czicman and Hoagland, 1961). These reports suggest that schizophrenia is a pathological mental condition resulting from some disorder of metabolism or of biochemical processes, and it would be logical to expect that this disorder would be most manifest as a disturbance of the neurological activity in the cerebrum—perhaps more specifically in the cerebral cortex—since the clinical picture in schizophrenia is primarily one of gross derangement of the processes of perception, attention and thinking.

Type
Research Article
Copyright
Copyright © Royal College of Psychiatrists, 1963 

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