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The Effect of Activation Procedures on Neuroleptic-Induced Akathisia

Published online by Cambridge University Press:  02 January 2018

W. Wolfgang Fleischhacker*
Affiliation:
Department of Biological Psychiatry
Carl H. Miller
Affiliation:
Department of Psychiatry, Innsbruck University Clinics, Anichstrasse 35, A-6020 Innsbruck, Austria
Christian Barnas
Affiliation:
Department of Psychiatry, Innsbruck University Clinics, Anichstrasse 35, A-6020 Innsbruck, Austria
Ken Bergmann
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
Robert Perovich
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
Jose Ma. J. Alvir
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
Jeffrey A. Lieberman
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
John M. Kane
Affiliation:
Hillside Hospital, Division of Long Island Jewish Medical Center, New York, USA
*
Correspondence

Abstract

Two studies have been performed to evaluate the effect of activation tasks on neuroleptic-induced akathisia (NIA). In the first sample (30 patients) we found a consistent increase of symptoms during mental activation while motor activation led to a decrease. In a second study 34 patients with the same diagnosis were evaluated, using slightly different statistical procedures: while the effects of motor activation were corroborated, mental activation did not change NIA. Since mental and motor activation are usually considered to increase tardive dyskinesia and Parkinsonism, these measures might be helpful in differentiating NIA from other antipsychotic-induced movement disorders.

Type
Research Article
Copyright
Copyright © The Royal College of Psychiatrists 

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