Published online by Cambridge University Press: 11 June 2020
How can we design and engineer research that leads to the development and effective implementation of complex healthcare interventions? We advocate for a systems design-based approach when initiating clinical research to anticipate the proposition of complex interventions. Using cognitive care as an example, we investigate how hybrid design-inspired methodologies can promote organisational effectiveness and how strong clinical evidence can support successful conceptualisation and uptake of novel interventions into routine clinical practice.