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Interactions between bacteria and the surface of the small intestine

Published online by Cambridge University Press:  24 November 2017

D. Kelly ,
R. Begbie ,
A.J. Flanagan ,
R.G. Mattison  and
T.P. King
D. Kelly
Affiliation:
Rowett Research Institute, BucksburnAberdeen AB2 9SB
R. Begbie
Affiliation:
Rowett Research Institute, BucksburnAberdeen AB2 9SB
A.J. Flanagan
Affiliation:
Rowett Research Institute, BucksburnAberdeen AB2 9SB
R.G. Mattison
Affiliation:
Rowett Research Institute, BucksburnAberdeen AB2 9SB
T.P. King
Affiliation:
Rowett Research Institute, BucksburnAberdeen AB2 9SB
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Extract

Many bacterial species are closely associated with epithelial surfaces of the gastrointestinal tract. The physicochemical interactions between bacteria and the intestinal surface are complex and include both stereospecific and chemotactic effects. Such mechanisms of interaction and attachment of bacteria to the gut have received considerable attention over the last decade as they have been recognised as an important initial event in colonisation and the pathogenesis of enteric infections. Many disease-causing bacteria possess surface fimbriae or fibrillae with lectin-like adhesins which interact with peptides or carbohydrates present on surface glycosphingolipids and/or glycoproteins. Research on the structural features of fimbrial receptors and on their expression on the surfaces of the mammalian intestine has led to new ideas for nutritional therapy and/or prophylaxis based on the prevention of adherence of pathogenic bacteria.

Type
Gut Microbiology
Information
Proceedings of the British Society of Animal Production (1972) , Volume 1993: Winter meeting , March 1993 , pp. 31
Copyright
Copyright © The British Society of Animal Production 1993

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