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Synthesis and Characterization of Tetraethylene Glycolpoly(Ethylene Oxide) Hydrogels for Tissue Engineering Applications

Published online by Cambridge University Press:  15 February 2011

A. T. Royappa
Affiliation:
Massachusetts Institute of Technology, Department of Chemical Engineering, 77 Massachusetts Avenue, Cambridge, MA 02139
S. T. Lopina
Affiliation:
Massachusetts Institute of Technology, Department of Chemical Engineering, 77 Massachusetts Avenue, Cambridge, MA 02139
L. G. Cima
Affiliation:
Massachusetts Institute of Technology, Department of Chemical Engineering, 77 Massachusetts Avenue, Cambridge, MA 02139
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Abstract

A new poly(ethylene oxide) based biomaterial has been synthesized by co-crosslinking linear poly(ethylene oxide) (PEO) with tetraethylene glycol (TEG) in aqueous solution using electron beam radiation. This process results in hydrogels with variable concentrations of hydroxyl groups, tunable by adjusting the concentration of TEG in solution. FTIR analysis of these gels shows no changes in chemical composition on crosslinking.

Type
Research Article
Copyright
Copyright © Materials Research Society 1994

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