Hostname: page-component-586b7cd67f-g8jcs Total loading time: 0 Render date: 2024-11-25T17:52:46.771Z Has data issue: false hasContentIssue false
  • English
  • Français

Synthesis and Characterization of Tetraethylene Glycolpoly(Ethylene Oxide) Hydrogels for Tissue Engineering Applications

Published online by Cambridge University Press:  15 February 2011

A. T. Royappa ,
S. T. Lopina  and
L. G. Cima
A. T. Royappa
Affiliation:
Massachusetts Institute of Technology, Department of Chemical Engineering, 77 Massachusetts Avenue, Cambridge, MA 02139
S. T. Lopina
Affiliation:
Massachusetts Institute of Technology, Department of Chemical Engineering, 77 Massachusetts Avenue, Cambridge, MA 02139
L. G. Cima
Affiliation:
Massachusetts Institute of Technology, Department of Chemical Engineering, 77 Massachusetts Avenue, Cambridge, MA 02139
Get access

Abstract

A new poly(ethylene oxide) based biomaterial has been synthesized by co-crosslinking linear poly(ethylene oxide) (PEO) with tetraethylene glycol (TEG) in aqueous solution using electron beam radiation. This process results in hydrogels with variable concentrations of hydroxyl groups, tunable by adjusting the concentration of TEG in solution. FTIR analysis of these gels shows no changes in chemical composition on crosslinking.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 331: Symposium T – Biomaterials for Drug and Cell Delivery , 1993 , 245
Copyright
Copyright © Materials Research Society 1994

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Cima, L. G., Vacanti, J. P., Vacanti, C., Ingber, D., Mooney, D. and Langer, R., J. Biomed. Eng. 113, 143 (1991).Google Scholar
2. Bruck, S. D., Biomat. Med. Dev., Artif. Organs 1, 79 (1973).Google Scholar
3. Merrill, E. W. and Salzman, E. W., J. Amer. Soc. Artif. Intern. Org. 6, 60 (1982).Google Scholar
4. Merrill, E. W., Salzman, E. W., Dennison, K. A., Tay, S.-W. and Pekala, R. W., Progress in Artificial Organs, Nosé, Y., Kjellstrand, C. & Ivanovich, P., eds., ISAO Press, Cleveland (1985).Google Scholar
5. Graham, N. B., Nwachuku, N. E. and Walsh, D. J., Preprints of the Informal Faraday Meeting, Cranfield Institute of Technology, 6–7 Jan. 1976.Google Scholar
6. Treloar, L. R. G., “Physics of Rubber Elasticity”, Oxford Univ. Press, London (1975).Google Scholar
7. Bray, J. C. and Merrill, E. W., J. Appl. Polym. Sci. 17, 3779 (1973).Google Scholar
8. Dennison, K. A., Ph. D. Thesis, Massachusetts Institute of Technology (1986).Google Scholar
9. Oka, J.A. and Weigel, P.H., J. Cell. Biol. 103, 1055–1060 (1986).Google Scholar