Since its creation in 1950, the Argentine Atomic Energy Commission (CNEA), has worked on the development of applications for the peaceful use of nuclear energy. They include, among others, research and development activities in basic and nuclear technology areas, the operation of important facilities for the production of radioisotopes and the performance of tasks in connection with the nuclear fuel cycle, mining and uranium processing activities, manufacturing of fuel elements, production of heavy water and the operation of two nuclear power plants. Also demonstrating reprocessing programs have been developed.

As a result of the above mentioned activities performed in the nuclear field by private and public entities, various types of radioactive waste have been and are produced during operation and maintenance of facilities and plants, and will be produced in their future decommissioning. CNEA is also responsible for the environmental remediation of the closed uranium mining and milling facilities and for the management of disused sealed sources from medical and industrial applications.

Activities concerning radioactive waste management are carried on according not only to Nuclear Regulatory Authority requirements and International Atomic Energy Agency recommendations, but also to the national legal framework.

The Law Nº 25.018, "Radioactive Waste Management Regime“(1998), created the National Program for Radioactive Waste Management (PNGRR), as part of CNEA organization.