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Peptide Nucleic Acid (PNA). a Structural DNA Mimic

Published online by Cambridge University Press:  15 February 2011

Peter E. Nielsen
Peter E. Nielsen*
Affiliation:
Research Center for Medical Biotechnology, Department of Medical Biochemistry & Genetics, Biochemistry Laboratory B, The Panum Institute, University of Copenhagen, Blegdarnsvej 3c, DK 2200 Copenhagen N, Denmark.
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Extract

Deoxyribonucleic acid (DNA) may be regarded as the central molecule of life since it is the carrier of genetic information; it is the chemical constituent of the genes. DNA is a biopolymer composed of deoxyribonucleoside units connected via phosphodiester bridges (Figure 1a). It is the linear order of the nucleobases (A, C, G & T) that contain the genetic information, whereas the deoxyribose phosphate backbone primarily fulfils a structural role.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 330: Symposium S – Biomolecular Materials by Design , 1993 , 3
Copyright
Copyright © Materials Research Society 1994

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References

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