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Hybrid Nanomaterial Scaffolds for Specific Biomedical Applications

Published online by Cambridge University Press:  31 January 2011

Mandar Gadre ,
Jianing Yang  and
Frederic Zenhausern
Mandar Gadre
Affiliation:
[email protected], Arizona State University, School of Materials, Tempe, Arizona, United States
Jianing Yang
Affiliation:
[email protected], University of Arizona, Center for Applied Nanobioscience & Medicine, Phoenix, Arizona, United States
Frederic Zenhausern
Affiliation:
[email protected], University of Arizona, Center for Applied Nanobioscience & Medicine, Phoenix, Arizona, United States
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Abstract

Highly porous nanomaterials like aerogels, hybrid crosslinked aerogels (X-aerogels) and xerogels exhibit a broad range of tailorable properties such as the pore size, surface area, surface chemistry and mechanical strength. The versatile manufacturing route of sol-gel synthesis and various tunable properties makes aerogels and xerogels attractive candidates for biomedical applications including tissue engineering, sample collection applicators and engineered microenvironments for three-dimensional cell culture. The present study explores meso- and macroporous inorganic-organic hybrid aerogels prepared via sol-gel processing for two different applications, namely, as scaffolds for cell culture and as potential materials for sample collection applicators.

Keywords

aerogelsol-gelbiomedical
Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 1237: Symposium TT – Nanobiotechnology and Nanobiophotonics - Opportunities and Challenges , 2009 , 1237-TT05-02
Copyright
Copyright © Materials Research Society 2010

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References

1 Brinker, C.J. Scherer, G. W. Sol-Gel Science: The Physics and Chemistry of Sol-Gel Processing, 1st ed. (Academic Press, New York, 1990).Google Scholar
2 Gibson, L. J. Ashby, M. F. Cellular Solids: Structure and Properties, 2nd ed. (Cambridge University Press, 1997).Google Scholar
3 Pierre, A. C. Pajonk, G. M. Chem. Rev., 102, 4243–4265 (2002).Google Scholar
4 Griffith, L. G. Swartz, M. A. Molecular Cell Biology Nature Reviews, Vol. 7, pp 211–224 (2006).Google Scholar
5 Zhang, S. Nature Biotechnology, Vol. 221, No. 2 (Feb 2004).Google Scholar
6 Zhang, S. Gelain, F. Zhao, X. Seminars in Cancer Biology 15, 413–420 (2005).Google Scholar
7 Peppas, N. Sefton, M. J. Advances in Chemical Engineering: Molecular and Cellular Foundations of Biomaterials, Elsevier Inc, (2004).Google Scholar
8 Murugan, R. Ramakrishna, S. Tissue Engineering, Vol. 13, No.8 (2007)Google Scholar
9 Leventis, N. Mulik, S. Wang, X. Dass, A. Patil, V. U. Sotiriou-Leventis, C., Lu, H. Churu, G. Capecelatro, A., J. of Non-Crystalline Solids, 354, 632–644 (2008).Google Scholar
10 Kanamori, K. Aizawa, M. Nakanishi, K. Hanada, T. J. Sol-Gel Sci Technol, 48: 172–181 (2008).Google Scholar