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Formation of Calcium Phosphate on Phosphorus-Containing Groups Introduced Substrate

Published online by Cambridge University Press:  10 February 2011

Y. Yokogawa ,
K. Nishizawa ,
F. Nagata  and
T. Kameyama
Y. Yokogawa
Affiliation:
National Industrial Research Institute of NAGOYA, 1-1 Hirate, Kita, NAGOYA, JAPAN
K. Nishizawa
Affiliation:
National Industrial Research Institute of NAGOYA, 1-1 Hirate, Kita, NAGOYA, JAPAN
F. Nagata
Affiliation:
National Industrial Research Institute of NAGOYA, 1-1 Hirate, Kita, NAGOYA, JAPAN
T. Kameyama
Affiliation:
National Industrial Research Institute of NAGOYA, 1-1 Hirate, Kita, NAGOYA, JAPAN
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Abstract

A calcium phosphate coating over chitin sample was produced by a process based on phosphorylation, Ca(OH)2 treatment and SBF immersion. Ca(OH)2 soaking of the fibers phosphorylated by urea/phosphorus acid (H3PO3) method is found to produce highly crystalline clusters lodged in the fibers which were calcium phosphite mono-hydrate (CaHPO3H2 O). CaHPO3H2O clusters were still present in chitin fibers even after 7 days of soaking, while after 17 days calcium phosphate was observed. While chitin fibers phosphorylated by urea and H3PO4 method and then soaked in saturated Ca(OH) 2 solution at ambient temperature, which lead to the formation of thin coatings formed by partial hydrolysis of PO4 functionalities which were found to stimulate the growth of a calcium phosphate coating on their surfaces after soaking in 1.5×SBF solution for as little as 1 day. EDX analyses of the thin coating gave Ca/P ratio of 1.29, which is speculated to be OCP. The mechanism of formation of the coating is believed to involve dissolution of the CaHPO3 H2O clusters or the OCP upon introduction of the Ca(OH) 2- treated phosphorylated chitin fibers into the 1.5×SBF solution which elevates the Ca2+ ion concentration in the vicinity of the fibers so stimulating calcium phosphate formation from the soaking medium.

Type
Research Article
Information
MRS Online Proceedings Library (OPL) , Volume 599: Symposium DD – Mineralization in Natural & Synthetic Biomaterials , 1999 , 311
Copyright
Copyright © Materials Research Society 2000

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