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Nanometrology and super-resolution imaging with DNA

Published online by Cambridge University Press:  08 December 2017

Elton Graugnard
Affiliation:
Micron School of Materials Science & Engineering, Boise State University, USA; [email protected]
William L. Hughes
Affiliation:
Micron School of Materials Science & Engineering, Boise State University, USA; [email protected]
Ralf Jungmann
Affiliation:
Ludwig Maximilian University Munich, Max Planck Institute of Biochemistry, Germany; [email protected]
Mauri A. Kostiainen
Affiliation:
School of Chemical Engineering, Aalto University, Finland; [email protected]
Veikko Linko
Affiliation:
School of Chemical Engineering, Aalto University, Finland; [email protected]
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Abstract

Structural DNA nanotechnology is revolutionizing the ways researchers construct arbitrary shapes and patterns in two and three dimensions on the nanoscale. Through Watson–Crick base pairing, DNA can be programmed to form nanostructures with high predictability, addressability, and yield. The ease with which structures can be designed and created has generated great interest for using DNA for a variety of metrology applications, such as in scanning probe microscopy and super-resolution imaging. An additional advantage of the programmable nature of DNA is that mechanisms for nanoscale metrology of the structures can be integrated within the DNA objects by design. This programmable structure–property relationship provides a powerful tool for developing nanoscale materials and smart rulers.

Type
Research Article
Copyright
Copyright © Materials Research Society 2017 

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