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Very tiny bar codes

Published online by Cambridge University Press:  14 March 2018

Stephen W. Carmichael*
Affiliation:
Mayo Clinic

Extract

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The use of barcodes on products, combined with the computer technology to read and track the subsequent data, has revolutionized inventory control in our society. Barcodes are commonly seen on items as large as automobiles and as small as pieces of candy. But if you need to track a large number of items that are microscopic in size, such as biologically relevant molecules (think genomics, proteomics, metabolomics, etc), then you need very small barcodes. Sufficiently small rods that can be marked as barcodes have been developed by Sheila Nicewarner-Peña, Griffith Freeman, Brian Reiss, Lin He, David Peña, Ian Walton, Remy Cromer, Christine Keating, and Michael Natan.

Type
Research Article
Copyright
Copyright © Microscopy Society of America 2002

Footnotes

1

The author gratefully acknowledges Dr, Christine D. Keating for reviewing this article.

References

2 Nicewarner-Peña, S.R., Freeman, R.G., Reiss, B.D., He, L., Peña, D.J., Walton, I.D., Cramer, R., Keating, C.D., and Natan, M.J., Submicrometer metallic barcodes, Science 294:137141, 2001.CrossRefGoogle ScholarPubMed
3 They used a Nikon TE-300 inverted microscope equipped with a brightfield reflectance filter, using 100X oil immersion lens, and a bandpass filter to vary the wavelength of the excitation beam.Google Scholar