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Laboratory Design for High-Performance Electron Microscopy

Published online by Cambridge University Press:  14 March 2018

Michael A. O'Keefe ,
John H. Turner ,
John A. Musante ,
Crispin J.D. Hetherington ,
A.G. Cullis ,
Bridget Carragher ,
Ron Jenkins ,
Julie Milgrim ,
Ronald A. Milligan  and
Clinton S. Potter
...Show all authors
Michael A. O'Keefe
Affiliation:
Lawence Berkeley National Laboratory, Berkeley, CA, USA
John H. Turner
Affiliation:
Lawence Berkeley National Laboratory, Berkeley, CA, USA
John A. Musante
Affiliation:
Lawence Berkeley National Laboratory, Berkeley, CA, USA
Crispin J.D. Hetherington
Affiliation:
Oxford University
A.G. Cullis
Affiliation:
The University of Sheffield, UK
Bridget Carragher
Affiliation:
The Scripps Research Institute, La Jolla, CA, USA
Ron Jenkins
Affiliation:
The Scripps Research Institute, La Jolla, CA, USA
Julie Milgrim
Affiliation:
The Scripps Research Institute, La Jolla, CA, USA
Ronald A. Milligan
Affiliation:
The Scripps Research Institute, La Jolla, CA, USA
Clinton S. Potter
Affiliation:
The Scripps Research Institute, La Jolla, CA, USA
Lawrence F. Allard
Affiliation:
High Temperature Materials Laboratory, ORNL, Oak Ridge, TN USA
Douglas A. Blom
Affiliation:
High Temperature Materials Laboratory, ORNL, Oak Ridge, TN USA
Lynn Degenhardt
Affiliation:
High Temperature Materials Laboratory, ORNL, Oak Ridge, TN USA
William H. Sides
Affiliation:
High Temperature Materials Laboratory, ORNL, Oak Ridge, TN USA

Extract

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Since publication of the classic text on the electron microscope laboratory by Anderson, the proliferation of microscopes with field emission guns, imaging filters and hardware spherical aberration correctors (giving higher spatial and energy resolution) has resulted in the need to construct special laboratories. As resolutions iinprovel transmission electron microscopes (TEMs) and scanning transmission electron microscopes (STEMs) become more sensitive to ambient conditions. State-of-the-art electron microscopes require state-of-the-art environments, and this means careful design and implementation of microscope sites, from the microscope room to the building that surrounds it. Laboratories have been constructed to house high-sensitive instruments with resolutions ranging down to sub-Angstrom levels; we present the various design philosophies used for some of these laboratories and our experiences with them. Four facilities are described: the National Center for Electron Microscopy OAM Laboratory at LBNL; the FEGTEM Facility at the University of Sheffield; the Center for Integrative Molecular Biosciences at TSRI; and the Advanced Microscopy Laboratory at ORNL.

Type
Research Article
Information
Microscopy Today , Volume 12 , Issue 3 , May 2004 , pp. 8 - 17
Copyright
Copyright © Microscopy Society of America 2004

References

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