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Visualization of intracellular Ebola virus nucleocapsid assembly by cryo-electron tomography

Published online by Cambridge University Press:  30 July 2021

Reika Watanabe ,
Guillaume Castillon ,
Ruben Diaz Avalos ,
Mark Ellisman  and
Erica Saphire
Reika Watanabe
Affiliation:
La Jolla Institute for Immunology, La Jolla, California, United States
Guillaume Castillon
Affiliation:
UCSD, United States
Ruben Diaz Avalos
Affiliation:
La Jolla Institute for Immunology, La Jolla, California, United States
Mark Ellisman
Affiliation:
UCSD, La Jolla, California, United States
Erica Saphire
Affiliation:
La Jolla Institute for Immunology, United States

Abstract

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Type
3D Structures: From Macromolecular Assemblies to Whole Cells (3DEM FIG)
Information
Microscopy and Microanalysis , Volume 27 , Supplement S1 , August 2021 , pp. 1708 - 1711
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Copyright
Copyright © The Author(s), 2021. Published by Cambridge University Press on behalf of the Microscopy Society of America

References

Baseler, L., Chertow, D. S., Johnson, K. M., Feldmann, H. & Morens, D. M. The Pathogenesis of Ebola Virus Disease. Annu. Rev. Pathol. 12, 387–418 (2017).Google ScholarPubMed
Ellis, D. S. et al. Ebola and Marburg viruses: II. Thier development within Vero cells and the extra-cellular formation of branched and torus forms. J. Med. Virol. 4, 213–225 (1979).CrossRefGoogle ScholarPubMed
Geisbert, T. W. & Jahrling, P. B. Differentiation of filoviruses by electron microscopy. Virus Res. 39, 129–150 (1995).Google ScholarPubMed
Noda, T. et al. Assembly and budding of Ebolavirus. PLoS Pathog. 2, e99 (2006).CrossRefGoogle ScholarPubMed
Olejnik, J., Ryabchikova, E., Corley, R. B. & Mühlberger, E. Intracellular events and cell fate in filovirus infection. Viruses 3, 1501–1531 (2011).CrossRefGoogle Scholar
Huang, Y., Xu, L., Sun, Y. & Nabel, G. J. The assembly of Ebola virus nucleocapsid requires virion-associated proteins 35 and 24 and posttranslational modification of nucleoprotein. Mol. Cell 10, 307–316 (2002).CrossRefGoogle ScholarPubMed
Bharat, T. A. M. et al. Structural dissection of Ebola virus and its assembly determinants using cryo-electron tomography. Proc. Natl. Acad. Sci. U. S. A. 109, 4275–4280 (2012).CrossRefGoogle ScholarPubMed